Buprenorphine is a semi-synthetic, partial opioid agonist used in Medication Assisted Treatment and opioid detox programs. Partial agonists bind to the given receptor, but have only partial efficacy compared with a full agonist such as methadone. It works by binding to the mu receptors which are responsible for opioid intoxication. Buprenorphine has a high affinity, but low intrinsic activity at the mu receptor, meaning it displaces other opioids, while having a less intoxicating effect.
Below are relevant news updates, policy updates, research documents on the topic of Buprenorphine. Looking for information on another topic? Search through our complete list of Clinical Resources and Operational Resources.
