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Key Statistics & Drugs of Abuse

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Drug misuse is the use of illegal drugs or the improper use of legal/prescribed drugs for a purpose other than what they were intended. When misused, the following common drugs may lead to physical, psychological, spiritual, and relational problems, as well as other drug-related risks. In some cases, substance use disorder (SUD) may develop.

To better understand the addiction to street or prescription drugs (or “substance use disorder,” as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) and how it is distinguished from physical dependency and drug tolerance, click here.

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Cannabis, commonly called Marijuana, is the most commonly used illicit drug (36.7 million users in the past year). Around 1 in ten marijuana users will develop a substance use disorder.[1] Also known as weed, MMJ, grass, pot, Mary Jane, and ganja, marijuana is a mind-altering, psychoactive drug that comes from the dried flowers, leaves, stems or seeds of the cannabis plant. Marijuana can be smoked in rolled cigarettes (joints) or cigar wraps (blunts); consumed through vaporization or water pipes (bongs); or consumed by oral ingestion (edibles), among other usage methods.

THC’s chemical structure mimics that of a natural brain chemical called endocannabinoids, which allows it to act on specific brain receptors. As marijuana overstimulates parts of the brain with high numbers of these brain receptors, it causes a “high” feeling. Effects vary by user, and may include:

  • Pleasant euphoria
  • Changes in mood
  • Altered senses (e.g. seeing brighter colors)
  • Altered sense of time
  • Difficulty with problem-solving
  • Memory impairment
  • Hallucinations, delusions, or psychosis (in high doses) [2]

People addicted to marijuana may have a higher risk of attention, memory, and learning problems with use. These negative brain effects are stronger when users choose marijuana with higher levels of tetrahydrocannabinol (THC). THC levels have been on the rise over the last few decades.[1]

Mental Health & Marijuana Use

According to a Centers for Disease Control and Prevention report, frequent (daily or near-daily) marijuana use may cause an individual to become anxious, paranoid, disoriented or plagued by unpleasant thoughts.[5] Long-term use of marijuana has been linked to mental illness in some users, which may include temporary paranoia and hallucinations or worsening schizophrenia symptoms in those already diagnosed.[4]

Considerations: Recreational Marijuana Legalization Impact

Further concerns about marijuana have emerged in states like Colorado, where recreational marijuana use was legalized in 2012. According to a 2018 report by the Rocky Mountain High-Intensity Drug Trafficking Area (HIDTA) Program, the following statistics have been reported since legalization:

  • 52% increase in the annual rate of emergency department visits
  • 148% increase in yearly marijuana-related hospitalizations
  • 151% increase in marijuana-related traffic deaths
  • 18.6% increase in violent crime
  • 8.3% increase in property crime [6]


More than 14 percent of Americans 12 and up have used cocaine, according to NIDA reports. Made from the leaves of the South American coca plant, cocaine (also known as crack, blow, coke, and snow) is a white, powdery drug. This highly addictive nervous-system stimulant speeds up the user’s body, increasing blood pressure and heart rate and boosting energy levels. As it floods the brain with the feel-good chemical dopamine, cocaine may also bring pleasure and euphoria to the user.[7]

Common cocaine use methods include, but are not limited to:

  • Snorted as powder
  • Applied topically to gums
  • Dissolved & injected into a vein
  • Inhaled as a heated crack crystal
  • Mixed with marijuana or tobacco & smoked

Cocaine’s effects may last from a few minutes to an hour, depending on how the drug is used. In addition to elevating energy levels and producing a feeling of happiness, the stimulant may make the user paranoid, irritable, or more sensitive to sound and light. Excessive drug doses may cause erratic, violent, and unpredictable behavior.[8]

Over time, people who snort cocaine may lose their sense of smell or have nosebleeds, as well as upper respiratory issues. Smoking crack can lead to asthma or pneumonia, while oral consumption may cause reduced blood flow to the bowel. Users who inject cocaine are at elevated risk for developing a soft-tissue infection or contracting Hepatitis C or HIV.[8]


A 2016 National Survey on Drug Use and Health (NSDUH) found that 948,000 Americans reported heroin use during the past year. This number has continued to rise since 2007, and heroin use is highest among young adults ages 18 to 25.[9]

Heroin (also called big H, hell dust, smack, and horse) is a synthetic opioid derived from morphine. Morphine comes from the seed pod of the opium poppy plant. Like cocaine, heroin may be a white powder. However, it comes in several other forms as well, including brown powder or black, sticky tar. Heroin users may choose to sniff, inject, snort, or smoke the drug.[10]

Prescription opioids like Vicodin® and Oxycontin® work similarly to heroin. Nearly 80 percent of Americans who use heroin report having misused prescription opioids first. Heroin binds to opioid receptors located in several areas of the brain, such as those that impact pain and pleasure or control critical body functions like sleeping, breathing, heart rate, and blood pressure.[10]

Heroin delivers a surge of pleasure at first, but users also report skin flushing, dry mouth, nausea and vomiting, clouded mentation, uncomfortable itching, and a heavy feeling in the limbs. In the long term, heroin users cite problems like these:

  • Chronic insomnia
  • Collapsed veins or damaged nasal tissue
  • Heart lining & valve infections
  • Abscesses
  • Liver & kidney disease
  • Lung & respiratory problems
  • Mental disorders
  • Sexual dysfunction or irregular menstruation

Heroin slows breathing, and large doses may induce a coma, cause permanent brain damage, or death.[10]


Methamphetamine (also known as crank, ice, chalk, or speed) is a stimulant that has a chemical structure similar to that of amphetamine (a drug used to treat attention-deficit hyperactivity disorder). Meth may appear in white powder or pill form or maybe crystallized (“crystal meth”). Methamphetamine users may inhale, snort, smoke, inject, or ingest.[11]

Methamphetamine users get instantly high, and the drug is commonly used in a succession of short-lasting “hits.” This meth binge-and-crash pattern may last for days, and often leads users to avoid food, sleep, or other critical life activities during binges.

Methamphetamine affects the brain by flooding it with dopamine (a natural chemical involved in the brain’s reward system). This dopamine surge makes the drug user want to engage in further drug-seeking and drug-taking behaviors to repeat the reward experience. In the short term, meth users may experience stimulant-induced effects like wakefulness and increased activity, rapid breathing and rapid heart rate. Over time, users who inject methamphetamine increase their risk of Hepatitis B and C, as well as HIV. Other negative physical and mental consequences include:

  • Major dental problems
  • Sores that develop from intense itching/scratching
  • Severe weight loss
  • Confusion & anxiety
  • Sleep issues
  • Paranoia & hallucinations
  • Violent tendencies [11]

Some recent research indicates that long-term methamphetamine use may lead to an increased risk of developing Parkinson’s disease, a movement disorder.[11]

Prescription Drugs

Misuse of prescription drugs often begins with proper prescribed use and devolves into an illegitimate, improper use of the drug over time. In some cases, users steal others’ prescription medications to manage pain or get high. This nonmedical use of prescription drugs may turn into a substance use disorder (SUD) or addiction over time.

Commonly misused and addictive prescription medications include:

  • Opioids: Usually prescribed for pain management 
  • Depressants: Common drugs include sedatives, tranquilizers, and hypnotics used to improve sleep or anxiety
  • Stimulants: Usually given to a patient for attention-deficit/hyperactivity disorder[12]

The United States is facing an opioid crisis. In 2017, the U.S. Department of Health and Human Services declared this crisis a “public health emergency” and issued a strategy to combat the epidemic.[14]

Prescription Drug Misuse Statistics

The statistics surrounding prescription drug misuse are daunting:

  • Around 18 million people have misused prescription drugs at least one time during the last year.[12]
  • The 2017 National Survey on Drug Use and Health reported that around two million Americans misused prescription pain relievers for the first time within the last year.[13]
  • Over one million Americans misused prescription stimulants, and 1.5 million misused tranquilizers for the first time within the last year.[13]
  • Prescription opioid-related overdose deaths were five times higher by 2016 than they were in 1999.[14]
  • Prescription drug misuse is highest among those ages 18 to 25; 14.4 percent reported using prescription drugs for nonmedical reasons in the past year.[12]

prescription drug addiction statistics

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Getting Professional Addiction Diagnosis & Treatment

To avoid what renowned scholar William White refers to as the U.S. arresting and incarcerating itself out of the addiction crisis, the National Association of Addiction Treatment Professionals supports it's members by providing clinical and operational resources as well as law and policy advocacy and encourages the delivery of quality treatment programs.

Click here to access the NAATP’s regularly updated Addiction Industry Directory (AID). This directory includes Association members in good standing and distinguished Accredited Providers. For more information about selecting a treatment provider, visit the NAATP’s Addiction & Treatment Resource section.

[1] “Health Effects | Marijuana | CDC.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention,
[2] National Institute on Drug Abuse. “Marijuana.” NIDA,
[3] “Health Effects | Marijuana | CDC.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention,
[4] National Institute on Drug Abuse. “Marijuana.” NIDA,
[5] National Academies of Sciences E, and Medicine. (2017). The health effects of cannabis and cannabinoids: Current state of evidence and recommendations for research Washington, D.C.
[6] “The Legalization of Marijuana in Colorado: The Impact (Volume 5).” Rocky Mountain High-Intensity Drug Trafficking Area, Sept. 2018,
[7] National Institute on Drug Abuse. “Cocaine.” NIDA,
[8] National Institute on Drug Abuse. “Cocaine.” NIDA,
[9] Substance Abuse Center for Behavioral Health Statistics and Quality. Results from the 2016 National Survey on Drug Use and Health: Detailed Tables. SAMHSA. Published September 7, 2017. Accessed March 7, 2018.
[10] National Institute on Drug Abuse. “Heroin.” NIDA,
[11] National Institute on Drug Abuse. “Methamphetamine.” NIDA,
[12] National Institute on Drug Abuse. “Summary of Misuse of Prescription Drugs.” NIDA,
[13] “2017 NSDUH Annual National Report.” 2017 NSDUH Annual National Report | CBHSQ,
[14] Centers for Disease Control and Prevention. Prescription Opioid Data. Published August 31, 2018. Accessed September 18, 2018.
[15] “Health Effects | Marijuana | CDC.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention,